<i>N</i>-Phenacyldibromobenzimidazoles—Synthesis Optimization and Evaluation of Their Cytotoxic Activity

<i>N</i>-Phenacyldibromobenzimidazoles—Synthesis Optimization and Evaluation of Their Cytotoxic Activity

Antifungal <i>N</i>-phenacyl derivatives of 4,6- and 5,6-dibromobenzimidazoles are interesting substrates in the synthesis of new antimycotics. Unfortunately, their application is limited by the low synthesis yields and time-consuming separation procedure. In this paper, we present the o...

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Bibliographic Details
Main Authors: Anna Kowalkowska, Konrad Chojnacki, Maciej Multan, Jan K. Maurin, Edyta Łukowska-Chojnacka, Patrycja Wińska
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
dibromobenzimidazoles
<i>N</i>-phenacyl
synthesis optimization
<i>N</i>-alkylation
cytotoxicity
cancer
Online Access:https://www.mdpi.com/1420-3049/27/14/4349

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https://www.mdpi.com/1420-3049/27/14/4349

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