Zebrafish Models of Rare Neurological Diseases like Spinocerebellar Ataxias (SCAs): Advantages and Limitations

Spinocerebellar ataxia (SCA) is a heterogeneous group of rare familial neurodegenerative disorders that share the key feature of cerebellar ataxia. Clinical heterogeneity, diverse gene mutations and complex neuropathology pose significant challenges for developing effective disease-modifying therapi...

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Bibliographic Details
Main Authors: Sreeja Sarasamma, Anwarul Karim, James P. Orengo
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/10/1322