Cardiac myosin binding protein-C phosphorylation as a function of multiple protein kinase and phosphatase activities

Cardiac myosin binding protein-C phosphorylation as a function of multiple protein kinase and phosphatase activities

Abstract Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) is a determinant of cardiac myofilament function. Although cMyBP-C phosphorylation by various protein kinases has been extensively studied, the influence of protein phosphatases on cMyBP-C’s multiple phosphorylation sites has rem...

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Bibliographic Details
Main Authors: Thomas Kampourakis, Saraswathi Ponnam, Kenneth S. Campbell, Austin Wellette-Hunsucker, Daniel Koch
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49408-5

Internet

https://doi.org/10.1038/s41467-024-49408-5

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