Structure of the human heparan sulfate polymerase complex EXT1-EXT2
Heparan sulfates are long and complex polysaccharides that mediate a large number of biological processes at the cell surface. Here, the authors provide structural and functional insights into the human EXT1-EXT2 complex that carries out the polymerization of heparan sulfate chains.
Bibliographic Details
| Main Authors: |
Francisco Leisico,
Juneina Omeiri,
Christine Le Narvor,
Joël Beaudouin,
Michael Hons,
Daphna Fenel,
Guy Schoehn,
Yohann Couté,
David Bonnaffé,
Rabia Sadir,
Hugues Lortat-Jacob,
Rebekka Wild |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-34882-6
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