Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair
How adhesive forces are transduced and integrated into biochemical signals at focal adhesions (FAs) is poorly understood. Here authors show that force- FAK signaling coupling coordinates cell migration and tissue-scale forces to promote microtissue repair.
Bibliographic Details
| Main Authors: |
Dennis W. Zhou,
Marc A. Fernández-Yagüe,
Elijah N. Holland,
Andrés F. García,
Nicolas S. Castro,
Eric B. O’Neill,
Jeroen Eyckmans,
Christopher S. Chen,
Jianping Fu,
David D. Schlaepfer,
Andrés J. García |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-22602-5
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