The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells

The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells

Febuxostat (FBX) is a drug able to inhibit xanthine oxidase and reduce uric acid production commonly used for the treatment of hyperuricemia in subjects suffering from gout. Several studies have also been directed at its use as anti-cancer drug during the last years, opening a window for its off-lab...

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Bibliographic Details
Main Authors: Usama A. Fahmy, Hibah M. Aldawsari, Shaimaa M. Badr-Eldin, Osama A. A. Ahmed, Nabil A. Alhakamy, Helal H. Alsulimani, Filippo Caraci, Giuseppe Caruso
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
febuxostat
emulsomes
drug release
apoptosis
necrosis
cytotoxicity
Online Access:https://www.mdpi.com/1999-4923/12/10/956

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https://www.mdpi.com/1999-4923/12/10/956

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