Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort.

Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort.

The mitochondrial genome encodes for the synthesis of 13 proteins that are essential for the oxidative phosphorylation (OXPHOS) system. Inherited variation in mitochondrial genes may influence cancer development through changes in mitochondrial proteins, altering the OXPHOS process, and promoting th...

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Bibliographic Details
Main Authors: Yuqing Li, Kenneth B Beckman, Christian Caberto, Remi Kazma, Annette Lum-Jones, Christopher A Haiman, Loïc Le Marchand, Daniel O Stram, Richa Saxena, Iona Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4560485?pdf=render

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http://europepmc.org/articles/PMC4560485?pdf=render

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