Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa

Abstract Background Despite the well-known detrimental effects of cigarette smoke (CS), little is known about the complex gene expression dynamics in the early stages after exposure. This study aims to investigate early transcriptomic responses following CS exposure of airway epithelial cells in cul...

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Bibliographic Details
Main Authors: Anne M. van der Does, Rashad M. Mahbub, Dennis K. Ninaber, Senani N. H. Rathnayake, Wim Timens, Maarten van den Berge, Hananeh Aliee, Fabian J. Theis, Martijn C. Nawijn, Pieter S. Hiemstra, Alen Faiz
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Respiratory Research
Online Access:https://doi.org/10.1186/s12931-022-02150-2