Inhibition of NETosis via PAD4 alleviated inflammation in giant cell myocarditis

Summary: Giant cell myocarditis (GCM) is a rare, usually rapidly progressive, and potentially fatal disease. Detailed inflammatory responses remain unknown, in particular the formation of multinucleate giant cells. We performed single-cell RNA sequencing analysis on 15,714 Cd45+ cells extracted from...

Full description

Bibliographic Details
Main Authors: Zhan Hu, Xiumeng Hua, Xiuxue Mo, Yuan Chang, Xiao Chen, Zhenyu Xu, Mengtao Tao, Gang Hu, Jiangping Song
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012397