25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism[S]

25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism[S]

Cholesterol 25-hydroxylase (CH25H) catalyzes the production of 25-hydroxycholesterol (25-HC), an oxysterol that can play an important role in different biological processes. However, the mechanisms regulating CH25H expression have not been fully elucidated. In this study, we determined that CH25H is...

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Bibliographic Details
Main Authors: Ying Liu, Zhuo Wei, Xingzhe Ma, Xiaoxiao Yang, Yuanli Chen, Lei Sun, Chuanrui Ma, Qing R. Miao, David P. Hajjar, Jihong Han, Yajun Duan
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Lipid Research
Subjects:
hepatocytes
25-hydroxycholesterol
interferon-γ
liver X receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331333

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http://www.sciencedirect.com/science/article/pii/S0022227520331333

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