Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy

Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy

Introduction: Fuchs endothelial corneal dystrophy (FECD) is the leading cause of corneal blindness in developed countries. Corneal endothelial cells in FECD are susceptive to oxidative stress, leading to mitochondrial dysfunction and cell death. Oxidative stress causes many forms of cell death inclu...

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Bibliographic Details
Main Authors: Saki Sakakura, Emi Inagaki, Tomoko Sayano, Risa Yamazaki, Noemi Fusaki, Shin Hatou, Masatoshi Hirayama, Kazuo Tsubota, Kazuno Negishi, Hideyuki Okano, Shigeto Shimmura
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Regenerative Therapy
Subjects:
Cell death
Fuchs' endothelial corneal dystrophy
Induced pluripotent stem cells
Oxidative stress
Parthanatos
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320423001062

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http://www.sciencedirect.com/science/article/pii/S2352320423001062

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