<u>S</u>mall <u>M</u>olecule <u>Ar</u>ranged <u>T</u>hermal <u>P</u>roximity <u>C</u>o<u>a</u>ggregation (smarTPCA)—A Novel Approach to Characterize Protein–Protein Interactions in Living Cells by Similar Isothermal Dose–Responses

Chemical biology and the application of small molecules has proven to be a potent perturbation strategy, especially for the functional elucidation of proteins, their networks, and regulators. In recent years, the cellular thermal shift assay (CETSA) and its proteome-wide extension, thermal proteome...

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Bibliographic Details
Main Authors: Thomas Lenz, Kai Stühler
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/10/5605