Radiosynthesis and Radiotracer Properties of a 7-(2-[18F]Fluoroethoxy)-6-methoxypyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET

Phosphodiesterase 10A (PDE10A) is a key enzyme of intracellular signal transduction which is involved in the regulation of neurotransmission. The molecular imaging of PDE10A by PET is expected to allow a better understanding of physiological and pathological processes related to PDE10A expression an...

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Bibliographic Details
Main Authors: Detlef Briel, Peter Brust, Achim Hiller, Gregor Schwan, Aurélie Maisonial, Matthias Scheunemann, Steffen Fischer, Winnie Deuther-Conrad, Uta Funke
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/5/2/169/