SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD.

SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD.

We applied single nucleotide polymorphism arrays (SNP-A) to study karyotypic abnormalities in patients with atypical myeloproliferative syndromes (MPD), including myeloproliferative/myelodysplastic syndrome overlap both positive and negative for the JAK2 V617F mutation and secondary acute myeloid le...

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Bibliographic Details
Main Authors: Lukasz P Gondek, Andrew J Dunbar, Hadrian Szpurka, Michael A McDevitt, Jaroslaw P Maciejewski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2075364?pdf=render

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http://europepmc.org/articles/PMC2075364?pdf=render

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