Identification and validation of diagnostic cut-offs of the ELISpot assay for the diagnosis of invasive aspergillosis in high-risk patients.

Identification and validation of diagnostic cut-offs of the ELISpot assay for the diagnosis of invasive aspergillosis in high-risk patients.

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<h4>Objective</h4>We investigated the performance of enzyme linked immunospot (ELISpot) assay for the diagnosis of invasive aspergillosis (IA) in high-risk patients with hematologic malignancies.<h4>Methods</h4>We prospectively enrolled two cohorts of patients undergoing inte...

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Bibliographic Details
Main Authors: Francesca Bettelli, Daniela Vallerini, Ivana Lagreca, Patrizia Barozzi, Giovanni Riva, Vincenzo Nasillo, Ambra Paolini, Roberto D'Amico, Fabio Forghieri, Monica Morselli, Valeria Pioli, Andrea Gilioli, Davide Giusti, Andrea Messerotti, Paola Bresciani, Angela Cuoghi, Elisabetta Colaci, Roberto Marasca, Livio Pagano, Anna Candoni, Johan Maertens, Pierluigi Viale, Cristina Mussini, Rossella Manfredini, Enrico Tagliafico, Mario Sarti, Tommaso Trenti, Russell Lewis, Patrizia Comoli, Albino Eccher, Mario Luppi, Leonardo Potenza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0306728

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https://doi.org/10.1371/journal.pone.0306728

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