Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.

Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.

RATIONALE:Perioperative myocardial ischemia is common in high-risk patients. The use of interventional revascularisation or even thrombolysis is limited in this patient subset due to exceedingly high bleeding risks. Blockade of voltage-gated sodium channels (VGSC) with lidocaine had been suggested t...

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Bibliographic Details
Main Authors: Björn Müller-Edenborn, Gabriela Kania, Elena Osto, Philipp Jakob, Nazmi Krasniqi, Beatrice Beck-Schimmer, Przemyslaw Blyszczuk, Urs Eriksson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4854463?pdf=render

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http://europepmc.org/articles/PMC4854463?pdf=render

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