The genetic landscape of a physical interaction

A key question in human genetics and evolutionary biology is how mutations in different genes combine to alter phenotypes. Efforts to systematically map genetic interactions have mostly made use of gene deletions. However, most genetic variation consists of point mutations of diverse and difficult t...

Full description

Bibliographic Details
Main Authors: Guillaume Diss, Ben Lehner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/32472