The pharmacological bases for repurposing statins in depression: a review of mechanistic studies

Abstract Statins are commonly prescribed medications widely investigated for their potential actions on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may play a role in the treatment of depressive disorders, but only the latter has been systematically assessed...

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Bibliographic Details
Main Authors: Riccardo De Giorgi, Nicola Rizzo Pesci, Gianluca Rosso, Giuseppe Maina, Philip J. Cowen, Catherine J. Harmer
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02533-z