Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma

Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma

Abstract The identification of BRAF V600 mutation in multiple cancers beyond melanoma and the development of combined BRAF and MEK targeting agents have altered the landscape of tissue-agnostic precision oncology therapies with an impact on survival outcomes. Despite initial efficacy, resistance eme...

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Detaylı Bibliyografya
Asıl Yazarlar: Blessie Elizabeth Nelson, Neha K. Reddy, Jason T. Huse, Behrang Amini, Mirella Nardo, Mohamed Gouda, Shiao-Pei Weathers, Vivek Subbiah
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Nature Portfolio 2023-05-01
Seri Bilgileri:npj Precision Oncology
Online Erişim:https://doi.org/10.1038/s41698-023-00398-5

Internet

https://doi.org/10.1038/s41698-023-00398-5

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