Differential response of IgM and IgG memory B cell populations to CD40L: insights of T cell – memory B cell interactions

Differential response of IgM and IgG memory B cell populations to CD40L: insights of T cell – memory B cell interactions

Memory B cells (mBCs) are characterized by their long-term stability, fast reactivation, and capability to rapidly differentiate into antibody-secreting cells (ASCs). However, the role of T cells in the differentiation of mBCs, in contrast to naive B cells, remains to be delineated. We study the rol...

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Bibliographic Details
Main Authors: Hector Rincon-Arevalo, Ana-Luisa Stefanski, Tuan Anh Le, Marcos Cases, Annika Wiedemann, Franziska Szelinski, Jacob Ritter, Van Duc Dang, Andreia C. Lino, Thomas Dörner, Eva Schrezenmeier
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Immunology
Subjects:
memory B cell
plasmablast
CD40L
plasma cell
T:B co-stimulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1432045/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1432045/full

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