Effect of methanol fixation on single-cell RNA sequencing of the murine dentate gyrus

Effect of methanol fixation on single-cell RNA sequencing of the murine dentate gyrus

Single-cell RNA sequencing (scRNA-seq) provides a powerful tool to evaluate the transcriptomic landscape and heterogeneity of thousands of cells in parallel. However, complex study designs or the unavailability of in-house instruments require the temporal disconnection between sample preparation and...

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Bibliographic Details
Main Authors: Marta Sánchez-Carbonell, Patricia Jiménez Peinado, Cathrin Bayer-Kaufmann, Jean-Christopher Hennings, Yvonne Hofmann, Silvio Schmidt, Otto W. Witte, Anja Urbach
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
methanol fixation
primary neural cells
SORT-seq
dentate gyrus
adult neurogenesis
single-cell RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1223798/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2023.1223798/full

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