Determination of Toxic Pyrrolizidine Alkaloids in Traditional Chinese Herbal Medicines by UPLC-MS/MS and Accompanying Risk Assessment for Human Health

Determination of Toxic Pyrrolizidine Alkaloids in Traditional Chinese Herbal Medicines by UPLC-MS/MS and Accompanying Risk Assessment for Human Health

Pyrrolizidine alkaloids (PAs) are a class of natural toxins with hepatotoxicity, genotoxicity and carcinogenicity. They are endogenous and adulterated toxic components widely found in food and herbal products. In this study, a sensitive and efficient ultra-high performance liquid chromatography-tand...

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Bibliographic Details
Main Authors: Junchi Wang, Meng Zhang, Lihua Chen, Yue Qiao, Siqi Ma, Dian Sun, Jianyong Si, Yonghong Liao
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
pyrrolizidine alkaloids
Chinese herbal medicines
estimated daily intake
Margin of exposure
risk assessment
Online Access:https://www.mdpi.com/1420-3049/26/6/1648

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https://www.mdpi.com/1420-3049/26/6/1648

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