Alternate-day fat diet and exenatide modulate the brain leptin JAK2/STAT3/SOCS3 pathway in a fat diet-induced obesity and insulin resistance mouse model

Introduction Obesity is one of the most burdensome health problems and is closely linked to leptin resistance. The study examined whether an alternate-day high-fat diet (ADF) and/or GLP-1 agonist (exenatide) modulate brain leptin resistance caused by a high-fat diet (HFD). Material and methods Sixt...

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Bibliographic Details
Main Authors: Mona K. Tawfik, Dahlia I. Badran, Mohammed M. Keshawy, Samy Makary, Mohamed Abdo
Format: Article
Language:English
Published: Termedia Publishing House 2023-02-01
Series:Archives of Medical Science
Subjects:
Online Access:https://www.archivesofmedicalscience.com/Alternate-day-fat-diet-and-exenatide-modulate-the-brain-leptin-JAK2-STAT3-SOCS3-pathway,158534,0,2.html