Lactobacillus gasseri LGV03 isolated from the cervico-vagina of HPV-cleared women modulates epithelial innate immune responses and suppresses the growth of HPV-positive human cervical cancer cells

Lactobacillus gasseri LGV03 isolated from the cervico-vagina of HPV-cleared women modulates epithelial innate immune responses and suppresses the growth of HPV-positive human cervical cancer cells

Persistent human papillomavirus (HPV) infections is necessary for the development of cervical cancers. An increasing number of retrospective studies have found the depletion of Lactobacillus microbiota in the cervico-vagina facilitate HPV infection and might be involved in viral persistence and canc...

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Bibliographic Details
Main Authors: Qiong Gao, Tao Fan, Siying Luo, Jieting Zheng, Lin Zhang, Longbing Cao, Zikang Zhang, Li Li, Zhu Huang, Huifen Zhang, Liuxuan Huang, Qing Xiao, Feng Qiu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Translational Oncology
Subjects:
HPV clearance
Lactobacillus gasseri LGV03
Antiviral immune response
IRF3 and NF-κB signaling
Common cervicovaginal microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323001006

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http://www.sciencedirect.com/science/article/pii/S1936523323001006

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