Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents

Abstract Background One-carbon metabolism, which includes the folate and methionine cycles, involves the transfer of methyl groups which are then utilised as a part of multiple physiological processes including redox defence. During the methionine cycle, the vitamin B12-dependent enzyme methionine s...

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Bibliographic Details
Main Authors: Alan D. Winter, Elissa Tjahjono, Leonardo J. Beltrán, Iain L. Johnstone, Neil J. Bulleid, Antony P. Page
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-022-01415-y