IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation

IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation

Abstract Background Among people living with HIV, elite controllers (ECs) maintain an undetectable viral load, even without receiving anti-HIV therapy. In non-EC patients, this therapy leads to marked improvement, including in immune parameters, but unlike ECs, non-EC patients still require ongoing...

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Bibliographic Details
Main Authors: Hélène Le Buanec, Valérie Schiavon, Marine Merandet, Alexandre How-Kit, Hongshuo Song, David Bergerat, Céline Fombellida-Lopez, Armand Bensussan, Jean-David Bouaziz, Arsène Burny, Gilles Darcis, Mohammad M. Sajadi, Shyamasundaran Kottilil, Daniel Zagury, Robert C. Gallo
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00453-7

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https://doi.org/10.1038/s43856-024-00453-7

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