Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells.

Claudin-2, ZO-1, and occludin are major components of tight junctions (TJs) in the proximal tubule. However, their roles in maintaining paracellular permeability as leaky epithelia have yet to be defined.To investigate the contributory role of TJ proteins in the leaky proximal tubule, we xamined the...

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Bibliographic Details
Main Authors: Sua Kim, Gheun-Ho Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5734727?pdf=render