A benchmarking protocol for intact protein-level Tandem Mass Tag (TMT) labeling for quantitative top-down proteomics

Isobaric chemical tag labeling for quantification of intact proteins in complex samples is limited due to the tendency of intact proteins precipitate under labeling conditions and increased sample complexity as a result of side products (i.e., incomplete labeling or labeling of unintended residues)....

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Yanting Guo, Dahang Yu, Kellye A. Cupp-Sutton, Xiaowen Liu, Si Wu
स्वरूप: लेख
भाषा:English
प्रकाशित: Elsevier 2022-01-01
श्रृंखला:MethodsX
विषय:
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S2215016122002527