Start Me Up: How Can Surrounding Gangliosides Affect Sodium-Potassium ATPase Activity and Steer towards Pathological Ion Imbalance in Neurons?

Start Me Up: How Can Surrounding Gangliosides Affect Sodium-Potassium ATPase Activity and Steer towards Pathological Ion Imbalance in Neurons?

Gangliosides, amphiphilic glycosphingolipids, tend to associate laterally with other membrane constituents and undergo extensive interactions with membrane proteins in <i>cis</i> or <i>trans</i> configurations. Studies of human diseases resulting from mutations in the ganglio...

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Bibliographic Details
Main Authors: Borna Puljko, Mario Stojanović, Katarina Ilic, Svjetlana Kalanj-Bognar, Kristina Mlinac-Jerkovic
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomedicines
Subjects:
glycosphingolipids
lipid rafts
membrane microdomains
neuronal ion homeostasis
GM1
Na<sup>+</sup>/K<sup>+</sup>-ATPase
Online Access:https://www.mdpi.com/2227-9059/10/7/1518

Internet

https://www.mdpi.com/2227-9059/10/7/1518

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