Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor.

Eukaryotic DNA polymerase δ (pol δ) plays a crucial role in chromosomal DNA replication and various DNA repair processes. It is thought to consist of p125, p66 (p68), p50 and p12 subunits. However, rigorous isolation of mammalian pol δ from natural sources has usually yielded two-subunit preparation...

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Bibliographic Details
Main Authors: Yajing Zhou, Huiqing Chen, Xiao Li, Yujue Wang, Keping Chen, Sufang Zhang, Xiao Meng, Ernest Y C Lee, Marietta Y W T Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3137619?pdf=render