Effects of Nalbuphine on Gastrointestinal Function in Post-Operative Critical Ill Patients Admitted to the ICU: A Multicenter Randomized Controlled Trial

BackgroundGastrointestinal (GI) function can be a significant problem in critically ill patients and is associated with detrimental outcomes. The administration of opioids for pain reduction is thought to contribute to GI dysfunction. We tested whether nalbuphine, a mixed agonist/antagonist opioid m...

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Bibliographic Details
Main Authors: Yun Yan, Chong Lei, Binxiao Su, Enxia Dong, Guangming Wang, Bin Li, Xinyu Li, Aiguang Li, Guifen Gan, Yu Chen, Xijing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.836872/full