M1-like, but not M0- or M2-like, macrophages, reduce RSV infection of primary bronchial epithelial cells in a media-dependent fashion.

Respiratory syncytial virus (RSV) is a common childhood infection that in young infants can progress into severe bronchiolitis and pneumonia. Disease pathogenesis results from both viral mediated and host immune processes of which alveolar macrophages play an important part. Here, we investigated th...

Full description

Bibliographic Details
Main Authors: Natalie J Ronaghan, Mandy Soo, Uriel Pena, Marisa Tellis, Wenming Duan, Nooshin Tabatabaei-Zavareh, Philipp Kramer, Juan Hou, Theo J Moraes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0276013