Study of the impact of different salts on the intrinsic dissolution rate of pharmaceutical compounds

The intrinsic dissolution rate (IDR) of a free base and its four salts were investigated with the aim of selecting the salt with the best dissolution performance. IDRs were measured using the Sirius inForm platform with quantitation by in-situ UV spectroscopy. Results showed that the hydrochloride s...

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Bibliographic Details
Main Authors: Karl Box, Rebeca Ruiz, Breeze Outhwaite, Sam Lee
Format: Article
Language:English
Published: University of Huddersfield Press 2017-12-01
Series:British Journal of Pharmacy
Subjects:
Online Access:https://www.bjpharm.org.uk/article/id/43/