Comparison of the structures and topologies of plasma extracted circulating nuclear and mitochondrial cell-free DNA

Comparison of the structures and topologies of plasma extracted circulating nuclear and mitochondrial cell-free DNA

Introduction: The function, origin and structural features of circulating nuclear DNA (cir-nDNA) and mitochondrial DNA (cir-mtDNA) are poorly known, even though they have been investigated in numerous clinical studies, and are involved in a number of routine clinical applications. Based on our previ...

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Bibliographic Details
Main Authors: Ekaterina Pisareva, Benoit Roch, Cynthia Sanchez, Brice Pastor, Alexia Mirandola, Mona Diab-Assaf, Thibault Mazard, Corinne Prévostel, Zahra Al Amir Dache, Alain R. Thierry
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Genetics
Subjects:
circulating DNA
mitochondria
whole genome sequencing
Q-PCR
diagnostics
structure
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1104732/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1104732/full

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