Gut Microbial Dysbiosis and Changes in Fecal Metabolic Phenotype in Precancerous Lesions of Gastric Cancer Induced With N-Methyl-N′-Nitro-N-Nitrosoguanidine, Sodium Salicylate, Ranitidine, and Irregular Diet

Gut Microbial Dysbiosis and Changes in Fecal Metabolic Phenotype in Precancerous Lesions of Gastric Cancer Induced With N-Methyl-N′-Nitro-N-Nitrosoguanidine, Sodium Salicylate, Ranitidine, and Irregular Diet

Background and Aims: Precancerous lesions of gastric cancer (PLGC) are the most important pathological phase with increased risk of gastric cancer (GC) and encompass the key stage in which the occurrence of GC can be prevented. In this study, we found that the gut microbiome changed significantly du...

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Bibliographic Details
Main Authors: Fuhao Chu, Yicong Li, Xiangmei Meng, Yuan Li, Tao Li, Mengyin Zhai, Haocheng Zheng, Tianxi Xin, Zeqi Su, Jie Lin, Ping Zhang, Xia Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Physiology
Subjects:
precancerous lesions of gastric cancer (PLGC)
gut microbial and metabolic dysbiosis
MNNG
16S rRNA genes sequencing
untargeted metabolomics analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.733979/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.733979/full

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