Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice

Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice

Abstract Cancer cachexia is a systemic metabolic syndrome characterized by involuntary weight loss, and muscle and adipose tissue wasting. Mechanisms underlying cachexia remain poorly understood. Leukemia inhibitory factor (LIF), a multi-functional cytokine, has been suggested as a cachexia-inducing...

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Bibliographic Details
Main Authors: Xue Yang, Jianming Wang, Chun-Yuan Chang, Fan Zhou, Juan Liu, Huiting Xu, Maria Ibrahim, Maria Gomez, Grace L. Guo, Hao Liu, Wei-Xing Zong, Fredric E. Wondisford, Xiaoyang Su, Eileen White, Zhaohui Feng, Wenwei Hu
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-44924-w

Internet

https://doi.org/10.1038/s41467-024-44924-w

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