NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation

NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation

Defective reactive oxygen species (ROS) production by genetically determined variants of the NADPH oxidase 2 (NOX2) complex component, NCF4, leads to enhanced production of autoantibodies to collagen type II (COL2) and severe collagen-induced arthritis (CIA) in mice. To further understand this proce...

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Bibliographic Details
Main Authors: Chang He, Huqiao Luo, Ana Coelho, Meng Liu, Qijing Li, Jing Xu, Alexander Krämer, Stephen Malin, Zuyi Yuan, Rikard Holmdahl
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Redox Biology
Subjects:
Neutrophil cytosolic factor 4
Redox regulation
B cell
Plasma cell
Autoimmunity
Oxidative eustress
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172200194X

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http://www.sciencedirect.com/science/article/pii/S221323172200194X

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