Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy

Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy

Chemotherapy remains the standard treatment for triple‐negative breast cancer (TNBC); however, chemoresistance compromises its efficacy. The RNA‐binding protein Hu antigen R (HuR) could be a potential therapeutic target to enhance the chemotherapy efficacy. HuR is known to mainly stabilize its targe...

Full description

Bibliographic Details
Main Authors: Lanjing Wei, Qi Zhang, Cuncong Zhong, Lily He, Yuxia Zhang, Ahlam M. Armaly, Jeffrey Aubé, Danny R. Welch, Liang Xu, Xiaoqing Wu
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Molecular Oncology
Subjects:
animal tumor model
chemoresistance
docetaxel
HuR
TNBC
Online Access:https://doi.org/10.1002/1878-0261.13478

Internet

https://doi.org/10.1002/1878-0261.13478

Similar Items