SIgA binding to mucosal surfaces is mediated by mucin-mucin interactions.

The oral mucosal pellicle is a layer of absorbed salivary proteins, including secretory IgA (SIgA), bound onto the surface of oral epithelial cells and is a useful model for all mucosal surfaces. The mechanism by which SIgA concentrates on mucosal surfaces is examined here using a tissue culture mod...

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Bibliographic Details
Main Authors: Hannah L Gibbins, Gordon B Proctor, Gleb E Yakubov, Stephen Wilson, Guy H Carpenter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368717?pdf=render