Polyglycerol-functionalized nanodiamond as a platform for gene delivery: Derivatization, characterization, and hybridization with DNA

Polyglycerol-functionalized nanodiamond as a platform for gene delivery: Derivatization, characterization, and hybridization with DNA

A gene vector consisting of nanodiamond, polyglycerol, and basic polypeptide (ND-PG-BPP) has been designed, synthesized, and characterized. The ND-PG-BPP was synthesized by PG functionalization of ND through ring-opening polymerization of glycidol on the ND surface, multistep organic transformations...

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Bibliographic Details
Main Authors: Li Zhao, Yuki Nakae, Hongmei Qin, Tadamasa Ito, Takahide Kimura, Hideto Kojima, Lawrence Chan, Naoki Komatsu
Format: Article
Language:English
Published: Beilstein-Institut 2014-03-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
carbon-nanomaterials
click chemistry
DNA
gene delivery
nanodiamond
polyglycerol
polypeptides
Online Access:https://doi.org/10.3762/bjoc.10.64

Internet

https://doi.org/10.3762/bjoc.10.64

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