Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut

Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut

The intestinal barrier is the main contributor to gut homeostasis. Perturbations of the intestinal epithelium or supporting factors can lead to the development of intestinal hyperpermeability, termed “leaky gut”. A leaky gut is characterized by loss of epithelial integrity and reduced function of th...

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Bibliographic Details
Main Authors: Michele d’Angelo, Laura Brandolini, Mariano Catanesi, Vanessa Castelli, Cristina Giorgio, Margherita Alfonsetti, Mara Tomassetti, Mara Zippoli, Elisabetta Benedetti, Maria Candida Cesta, Sandro Colagioia, Pasquale Cocchiaro, Annamaria Cimini, Marcello Allegretti
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
inflammation
oxidative stress
anti-inflammatory
macrophages
transepithelial electrical resistance
tight junction
Online Access:https://www.mdpi.com/2073-4409/12/5/728

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https://www.mdpi.com/2073-4409/12/5/728

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