Anti-Inflammatory, Antioxidant, and WAT/BAT-Conversion Stimulation Induced by Novel PPAR Ligands: Results from Ex Vivo and In Vitro Studies

Anti-Inflammatory, Antioxidant, and WAT/BAT-Conversion Stimulation Induced by Novel PPAR Ligands: Results from Ex Vivo and In Vitro Studies

Activation of peroxisome proliferator-activated receptors (PPARs) not only regulates multiple metabolic pathways, but mediates various biological effects related to inflammation and oxidative stress. We investigated the effects of four new PPAR ligands containing a fibrate scaffold—the PPAR agonists...

ver descrição completa

Detalhes bibliográficos
Principais autores: Lucia Recinella, Barbara De Filippis, Maria Loreta Libero, Alessandra Ammazzalorso, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Letizia Giampietro, Serena Veschi, Alessandro Cama, Federica Mannino, Irene Gasparo, Alessandra Bitto, Rosa Amoroso, Luigi Brunetti, Sheila Leone
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2023-02-01
coleção:Pharmaceuticals
Assuntos:
adipose tissue
UCP1
PPAR modulators
obesity
Acesso em linha:https://www.mdpi.com/1424-8247/16/3/346

Internet

https://www.mdpi.com/1424-8247/16/3/346

Registros relacionados