How alginate properties influence in situ internal gelation in crosslinked alginate microcapsules (CLAMs) formed by spray drying.

Alginates gel rapidly under ambient conditions and have widely documented potential to form protective matrices for sensitive bioactive cargo. Most commonly, alginate gelation occurs via calcium mediated electrostatic crosslinks between the linear polyuronic acid polymers. A recent breakthrough to f...

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Bibliographic Details
Main Authors: Tina Jeoh, Dana E Wong, Scott A Strobel, Kevin Hudnall, Nadia R Pereira, Kyle A Williams, Benjamin M Arbaugh, Julia C Cunniffe, Herbert B Scher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247171