Hereditary and Sporadic Forms of Aβ-Cerebrovascular Amyloidosis and Relevant Transgenic Mouse Models

Hereditary and Sporadic Forms of Aβ-Cerebrovascular Amyloidosis and Relevant Transgenic Mouse Models

Cerebral amyloid angiopathy (CAA) refers to the specific deposition of amyloid fibrils in the leptomeningeal and cerebral blood vessel walls, often causing secondary vascular degenerative changes. Although many kinds of peptides are known to be deposited as vascular amyloid, amyloid-β (Aβ)-CAA is th...

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Bibliographic Details
Main Author: Samir Kumar-Singh
Format: Article
Language:English
Published: MDPI AG 2009-04-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
cerebrovascular amyloidosis
CAA
dense-core plaques
senile plaques
amyloid β protein
transgenic mice
pathogenesis
therapy
Online Access:http://www.mdpi.com/1422-0067/10/4/1872/

Internet

http://www.mdpi.com/1422-0067/10/4/1872/

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