RAGE Differentially Altered in vitro Responses in Vascular Smooth Muscle Cells and Adventitial Fibroblasts in Diabetes-Induced Vascular Calcification

RAGE Differentially Altered in vitro Responses in Vascular Smooth Muscle Cells and Adventitial Fibroblasts in Diabetes-Induced Vascular Calcification

The Advanced Glycation End-Products (AGE)/Receptor for AGEs (RAGE) signaling pathway exacerbates diabetes-mediated vascular calcification (VC) in vascular smooth muscle cells (VSMCs). Other cell types are involved in VC, such as adventitial fibroblasts (AFBs). We hope to elucidate some of the mechan...

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Bibliographic Details
Main Authors: Amber M. Kennon, James A. Stewart
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
AGEs
RAGE
vascular smooth muscle cells
adventitial fibroblasts
diabetes mellitus
vascular calcification
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.676727/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.676727/full

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