Effects of Different Doses of Esketamine on Pain Sensitivity of Patients Undergoing Thyroidectomy: A Randomized Controlled Trial

Abstract Introduction Several factors may lead to increased postoperative pain sensitivity, of which remifentanil-induced hyperalgesia (RIH) is one of the main factors. High-dose remifentanil exposure during anesthesia may induce RIH. Esketamine may prevent RIH by antagonizing N-methyl-d-aspartate (...

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Bibliographic Details
Main Authors: Yan-ling Ren, Jing-jing Yuan, Fei Xing, Li-ning Zhu, Wei Zhang
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-03-01
Series:Pain and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s40122-023-00488-z