Deficiency of leukocyte-specific protein 1 (LSP1) alleviates asthmatic inflammation in a mouse model

Deficiency of leukocyte-specific protein 1 (LSP1) alleviates asthmatic inflammation in a mouse model

Abstract Background Asthma is a major cause of morbidity and mortality in humans. The mechanisms of asthma are still not fully understood. Leukocyte-specific protein-1 (LSP-1) regulates neutrophil migration during acute lung inflammation. However, its role in asthma remains unknown. Methods An OVA-i...

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Bibliographic Details
Main Authors: Nguyen Phuong Khanh Le, Amanda Florentina do Nascimento, David Schneberger, Chi Cuong Quach, Xiaobei Zhang, Gurpreet K. Aulakh, Wojciech Dawicki, Lixin Liu, John R. Gordon, Baljit Singh
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Respiratory Research
Subjects:
Macrophages
Leukocytes
LSP1
Asthma model
Online Access:https://doi.org/10.1186/s12931-022-02078-7

Internet

https://doi.org/10.1186/s12931-022-02078-7

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