Loss of Lipid Carrier ApoE Exacerbates Brain Glial and Inflammatory Responses after Lysosomal GBA1 Inhibition
Tightly regulated and highly adaptive lipid metabolic and transport pathways are critical to maintaining brain cellular lipid homeostasis and responding to lipid and inflammatory stress to preserve brain function and health. Deficits in the lipid handling genes <i>APOE</i> and <i>G...
Main Authors: | Kyle J. Connolly, Juliette Margaria, Erika Di Biase, Oliver Cooper, Penelope J. Hallett, Ole Isacson |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/12/21/2564 |
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