Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain

Background: Microglia, the brain's principal immune cell, are increasingly implicated in Alzheimer's disease (AD), but the molecular interfaces through which these cells contribute to amyloid beta (Aβ)-related neurodegeneration are unclear. We recently identified microglial contributions t...

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Bibliographic Details
Main Authors: Joshua D. Crapser, Elizabeth E. Spangenberg, Rocio A. Barahona, Miguel A. Arreola, Lindsay A. Hohsfield, Kim N. Green
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302942