Transcriptomic profiling of microglia and astrocytes throughout aging

Abstract Background Activation of microglia and astrocytes, a prominent hallmark of both aging and Alzheimer’s disease (AD), has been suggested to contribute to aging and AD progression, but the underlying cellular and molecular mechanisms are largely unknown. Methods We performed RNA-seq analyses o...

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Bibliographic Details
Main Authors: Jie Pan, Nana Ma, Bo Yu, Wei Zhang, Jun Wan
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-020-01774-9