Transcriptomic profiling of microglia and astrocytes throughout aging
Abstract Background Activation of microglia and astrocytes, a prominent hallmark of both aging and Alzheimer’s disease (AD), has been suggested to contribute to aging and AD progression, but the underlying cellular and molecular mechanisms are largely unknown. Methods We performed RNA-seq analyses o...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-020-01774-9 |